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81253

Sigma-Aldrich

Poly(éthylène glycol)

BioUltra, for molecular biology, 6,000

Synonyme(s) :

PEG

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About This Item

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
25322-68-3
Numéro MDL:
MFCD00081839
Code UNSPSC :
12352104
ID de substance PubChem :
24887713
Nomenclature NACRES :
NA.26

Qualité

for molecular biology

Gamme de produits

BioUltra

Forme

solid

Poids mol.

Mr 5000-7000

Impuretés

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

Solubilité

H2O: 50 mg/mL at 20 °C, clear, colorless

Traces d'anions

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

Traces de cations

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

Absorption UV

λ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.10

Adéquation

suitable for (molecular biology applications)

Chaîne SMILES 

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Description générale

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.

Application

Poly(ethylene glycol) has been used for concentrating HIV (human immunodeficiency virus). It has been used in the solution prepared to study CD (circular dichroism) spectra of nisin.

Autres remarques

Preparing phage and plasmid DNA - precipitation of λ phage; Fractionation of DNA fragments

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Fractionation of DNA fragments by polyethylene glycol induced precipitation.
J T Lis
Methods in enzymology, 65(1), 347-353 (1980-01-01)
Peini Hou et al.
Structure (London, England : 1993), 27(5), 837-845 (2019-03-05)
The evolutionarily conserved Trithorax group protein Ash1 is a SET domain histone methyltransferase that mono- and dimethylates lysine 36 of histone H3 (H3K36). Ash1 forms a complex with Mrg15 and Nurf55, and the binding of Mrg15 greatly stimulates the catalytic
Nisin antimicrobial activity and structural characteristics at hydrophobic surfaces coated with the PEO?PPO?PEO triblock surfactant Pluronic? F108.
Tai Y-C, et al.
Journal of Colloid and Interface Science, 322, 104-111 (2008)
Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice.
Singh VB, et al.
Scientific Reports, 6, doi: 10-doi: 10 (2016)
Benjamin J Burwitz et al.
Journal of immunology (Baltimore, Md. : 1950), 204(8), 2169-2176 (2020-03-13)
Currently 247 million people are living with chronic hepatitis B virus infection (CHB), and the development of novel curative treatments is urgently needed. Immunotherapy is an attractive approach to treat CHB, yet therapeutic approaches to augment the endogenous hepatitis B
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Contenu apparenté

Polyethylene Glycol (PEG) Selection Guide

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene Glycol (PEG) Selection Guide

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene Glycol (PEG) Selection Guide

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene Glycol (PEG) Selection Guide

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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