P2139

Poly(éthylène glycol)

average M_N 8,000, hydroxyl

• Synonyme(s) : PEG
• Formule linéaire : H(OCH₂CH₂)_nOH
• Numéro CAS: 25322-68-3
• UNSPSC Code: 12352104
• PubChem Substance ID: 24898275
• NACRES: NA.23
• MDL number: MFCD00081839

Propriétés

• Nom du produit: Poly(éthylène glycol), average mol wt 8,000, powder or flakes
• Quality Segment: 200
• form: powder or flakes
• mol wt: average mol wt 8,000
• greener alternative product characteristics: Safer Solvents and Auxiliaries; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product, Sustainability features
• solubility: water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)
• density: 1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C
• Ω-end: hydroxyl
• α-end: hydroxyl
• greener alternative category: , Aligned
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.

PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.

PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.

Features and Benefits

• Highstructural flexibility
• Biocompatibility
• Amphiphilicity
• Highhydration capacity
• Devoidof any steric hindrance

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)