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Key Documents

16702

Sigma-Aldrich

(R)-Pantetheine

≥95.0% (HPLC)

Synonyme(s) :

(2R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutanamide, (R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)carbamoyl]ethyl]-3,3-dimethylbutyramide, (D)-(+)-Pantetheine, N-(Pantothenyl)-β-aminoethanethiol, LBF, Lactobacillus bulgaricus factor

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About This Item

Formule empirique (notation de Hill):
C11H22N2O4S
Numéro CAS:
Poids moléculaire :
278.37
Numéro Beilstein :
1714196
Numéro MDL:
Code UNSPSC :
12352205
ID de substance PubChem :
Nomenclature NACRES :
NA.79

Niveau de qualité

Pureté

≥95.0% (HPLC)

Forme

solid

Activité optique

[α]/D 17±2°, c = 1 in H2O

Couleur

white

Température de stockage

−20°C

Chaîne SMILES 

OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O

InChI

1S/C11H22N2O4S/c1-11(2,7-14)9(16)10(17)13-4-3-8(15)12-5-6-18/h9,14,16,18H,3-7H2,1-2H3,(H,12,15)(H,13,17)/t9-/m0/s1

Clé InChI

ZNXZGRMVNNHPCA-VIFPVBQESA-N

Application


  • Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis: This study investigates the structural and dynamic aspects of carboxylic acid reductase enzymes, which are relevant for the conversion processes involving (R)-pantetheine and related compounds (Gahloth et al., 2017).

Actions biochimiques/physiologiques

Metabolite in carbapenem biosynthesis, pantothenate and CoA biosynthesis and biosynthesis of secondary metabolites.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

C T Wittwer et al.
The Journal of biological chemistry, 258(16), 9733-9738 (1983-08-25)
A microsomal glycoprotein that catalyzes the hydrolysis of pantetheine to pantothenate and cysteamine was solubilized and purified to homogeneity as determined by sodium dodecyl sulfate electrophoresis. The enzyme from pig kidney cortex was solubilized on exposure to butanol and purified
Jun Yang et al.
Applied optics, 57(10), 2490-2498 (2018-05-02)
On-site measurements and defect detection are of great importance for precision ground steel rollers due to their large dimension and weight. In addition to dimensional error, form accuracy, surface roughness, and surface/sub-surface cracks, there also exist optical defect requirements for
H Kleinkauf et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(9), 2069-2072 (1971-09-01)
To study the function of pantetheine in gramicidin S and tyrocidine biosynthesis, pepsin digests of the polymerizing enzymes, of which only the heavy ones contain pantetheine, were analyzed. The digests of gramicidin S enzymes charged with either [(14)C]proline or with
Laura B Ferguson et al.
Molecular neurobiology, 56(4), 2791-2810 (2018-08-01)
Alcohol use disorder (AUD) is a complex psychiatric disorder with strong genetic and environmental risk factors. We studied the molecular perturbations underlying risky drinking behavior by measuring transcriptome changes across the neurocircuitry of addiction in a genetic mouse model of
Judith Díaz-García et al.
Medical mycology, 58(7), 887-895 (2020-02-06)
The capacity of Candida spp. to form biofilms allows them to attach either to living or inert surfaces, promoting their persistence in hospital environments. In a previous study, we reported strain-to-strain variations in Candida spp. biofilm development, suggesting that some

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