P8074

TWEEN^® 80

BioXtra, viscous liquid

• Synonyme(s) : Mono-oléate de polyoxy-éthylènesorbitane, Mono-oléate de polyéthylène glycol sorbitane, Monooléate de POE (20)-sorbitane, Polysorbate 80
• Numéro CAS: 9005-65-6
• Numéro MDL: MFCD00082107
• Code UNSPSC : 12161900
• Nomenclature NACRES : NA.21

Propriétés

• Description: non-ionic
• Niveau de qualité: 200
• Gamme de produits: BioXtra
• Forme: viscous liquid
• Poids mol.: micellar avg mol wt 79,000; average mol wt 1310
• Composition: Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)
• Nombre d'agrégation: 60
• Technique(s): DNA extraction: suitable; RNA extraction: suitable; cell culture | mammalian: suitable; protein purification: suitable
• Impuretés: ≤0.025% Phosphorus (P)
• Résidus de calcination: <0.1%
• CMC: 0.012 mM (20-25°C)
• Température de transition: cloud point 65 °C
• Densité: 1.06 g/mL at 25 °C
• Traces d'anions: chloride (Cl^-): <0.05%; sulfate (SO₄^2-): <0.05%
• Traces de cations: Al: <0.0005%; Ca: <0.001%; Cu: <0.0005%; Fe: <0.0005%; K: <0.005%; Mg: <0.0005%; NH₄⁺: <0.05%; Na: <0.05%; Pb: <0.001%; Zn: <0.0005%
• HLB: 15
• Chaîne SMILES: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
• Clé InChI: RGPBUVUVZKQNHD-MDZDMXLPSA-N

Description

Description générale

["TWEEN"] 80 is a polyethylene sorbitol ester, broadly used in biochemical applications like solubilizing proteins, isolating nuclei from cells in culture, and growing tubercle bacilli. It is also useful in emulsifying and dispersing substances in medicinal and food products. TWEEN 80 acts as an active drying agent in ice cream.

Application

["TWEEN"] 80 has been used:

• to dissolve rapamycin (RAPA) for immunosuppressive treatment to perform in vivo studies in mice
• to dissolve remodelin and remodelin Fluor to assess remodelin toxicity in vivo and small molecule dosing
• to prepare assay medium for the microbiological assay for total folate

Informations légales

TWEEN is a registered trademark of Croda International PLC

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): >235.4 °F - closed cup
• Point d'éclair (°C): > 113 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves