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A0040000

Acebutolol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide

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About This Item

Formule empirique (notation de Hill):
C18H28N2O4 · HCl
Numéro CAS:
34381-68-5
Poids moléculaire :
372.89
Numéro MDL:
MFCD00078860
Code UNSPSC :
41116107
ID de substance PubChem :
329770566
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

acebutolol

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cl.CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(C)=O

InChI

1S/C18H28N2O4.ClH/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3;/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23);1H

Clé InChI

KTUFKADDDORSSI-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB1(153)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acebutolol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1000601

Acebutolol hydrochloride, United States Pharmacopeia (USP) Reference Standard

1000612

Acebutolol Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0000127

Acebutolol impurity C, European Pharmacopoeia (EP) Reference Standard

Y0000128

Acebutolol impurity I, European Pharmacopoeia (EP) Reference Standard

Y0000359

Acebutolol impurity B, European Pharmacopoeia (EP) Reference Standard

1000699

Acebutolol Related Compound I, United States Pharmacopeia (USP) Reference Standard

1000623

Acebutolol Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR2824

Acebutolol Related Compound A

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H312 + H332

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Donatella Ottaviani et al.
Journal of medical microbiology, 62(Pt 1), 161-164 (2012-09-25)
We report a severe case of travellers' diarrhoea in a patient returning from Ecuador to Italy with the concomitant presence of Aeromonas veronii biovar sobria and Vibrio parahaemolyticus in their faeces. Based on diagnostic results, epidemiological information and the clinical
Angela Yu-Chen Lin et al.
Journal of hazardous materials, 183(1-3), 242-250 (2010-08-11)
Sorption and combined sorption-biodegradation experiments were conducted in laboratory batch studies with 100 g soil/sediments and 500 mL water to investigate the fates in aqueous environments of acetaminophen, caffeine, propranolol, and acebutolol, four frequently used and often-detected pharmaceuticals. All four
Suguru Kurokawa et al.
Journal of nutritional science and vitaminology, 57(4), 298-305 (2011-11-02)
Selenocysteine lyase (SCL) catalyzes the decomposition of L-selenocysteine to yield L-alanine and selenium by acting exclusively on l-selenocysteine. The X-ray structural analysis of rat SCL has demonstrated how SCL discriminates L-selenocysteine from L-cysteine on the molecular basis. SCL has been
Natalia Hassan et al.
Colloids and surfaces. B, Biointerfaces, 82(2), 581-587 (2010-11-13)
The complex formed due to the interaction of the amphiphilic betablocker acebutolol with fibrinogen in a buffer solution (50mN glycine, pH of 8.5) has been investigated using a multipronged physicochemical approach. Differential scanning calorimetry measurements of the complexes have shown
Iu M Alekseeva et al.
Kardiologiia, 47(12), 24-34 (2008-02-12)
Beta-blocking agents (BB) decrease mortality particularly sudden in post-myocardial infarction patients and in patients with chronic heart failure that is closely related to heart rate (HR) lowering at rest. The hypothesis exists that BB decrease mortality due to increase of
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