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69311

Supelco

Quinine

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonyme(s) :

6′-Methoxycinchonidine

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About This Item

Formule empirique (notation de Hill):
C20H24N2O2
Numéro CAS:
Poids moléculaire :
324.42
Numéro Beilstein :
91867
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
TraceCERT®

Niveau de qualité

Gamme de produits

TraceCERT®

Durée de conservation

limited shelf life, expiry date on the label

Fabricant/nom de marque

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Conditions de stockage

under inert gas

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

173-175 °C (lit.)

Application(s)

food and beverages

Format

neat

Chaîne SMILES 

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1

Clé InChI

LOUPRKONTZGTKE-WZBLMQSHSA-N

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Description générale

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Potassium channel blocker

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Attention

Store under argon.

Informations légales

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Annemarie R Kreeftmeijer-Vegter et al.
Malaria journal, 12, 115-115 (2013-03-30)
Exchange transfusion (ET) has remained a controversial adjunct therapy for the treatment of severe malaria. In order to assess the relative contribution of ET to parasite clearance in severe malaria, all patients receiving ET as an adjunct treatment to parenteral
André Felipe Cândido da Silva et al.
Medical history, 58(1), 1-26 (2013-12-18)
This article addresses the discussion about quinine-resistant malaria plasmodium in the early decades of the twentieth century. Observed by Arthur Neiva in Rio de Janeiro in 1907, the biological and social resistance of malaria sufferers to preventive and curative treatment
Joop E Arends et al.
The American journal of tropical medicine and hygiene, 89(3), 527-530 (2013-07-17)
Recently, two patients of African origin were given a diagnosis of Plasmodium falciparum malaria without recent travel to a malaria-endemic country. This observation highlights the importance for clinicians to consider tropical malaria in patients with fever. Possible transmission routes of
Jane Achan et al.
Malaria journal, 10, 144-144 (2011-05-26)
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs. This
George Praygod et al.
Malaria journal, 7, 210-210 (2008-10-22)
The efficacy of intravenous quinine, which is the mainstay for treating severe malaria in children, is decreasing in South East Asia and Africa. Artemisinin derivatives are a potential alternative to quinine. However, their efficacy compared to quinine in treating severe

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