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34012

Supelco

Fluoxétine hydrochloride

VETRANAL®, analytical standard

Synonyme(s) :

(±)-N-Méthyl-γ-[4-(trifluorométhyl)phénoxy]benzènepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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About This Item

Formule empirique (notation de Hill):
C17H18F3NO · HCl
Numéro CAS:
Poids moléculaire :
345.79
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

Clé InChI

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Informations sur le gène

human ... SLC6A4(6532)

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Description générale

Fluoxetine hydrochloride is an antidepressant drug and a selective serotonin reuptake inhibitor, which is widely used for the treatment of major depressive disorders, obsessive-compulsive disorder and panic fits.

Application

Fluoxetine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological fluids using various chromatography techniques.
Fluoxetine hydrochloride may be used as an antidepressant, since it can selectively inhibit the serotonin uptake in the brain. It may also be used in the management of a variety of psychiatric and metabolic derangements.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Inhibiteur sélectif de la recapture de la sérotonine ; antidépresseur.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

Vendu sous licence de Eli Lilly and Co.
Prozac is a registered trademark of Eli Lilly and Co.
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Study of the interaction between fluoxetine hydrochloride and bovine serum albumin in the imitated physiological conditions by multi-spectroscopic methods
Katrahalli U, et al.
Journal of Luminescence, 130, 211-216 (2010)
Molecular Structure of Fluoxetine Hydrochloride, a Highly Selective Serotonin-Uptake Inhibitor
Robertson.WD, et al.
Journal of Medicinal Chemistry, 31, 185-189 (1988)
A rapid HPLC-DAD method for the analysis of fluoxetine and norfluoxetine in plasma from overdose patients.
Sabbioni C, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(2), 351-356 (2004)
LC-MS determination and bioavailability study of loperamide hydrochloride after oral administration of loperamide capsule in human volunteers.
Yu H-J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(2), 421-427 (2004)
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we

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