5.06382

MPTP Hydrochloride

≥98% (TLC), solid, dopaminergic neurotoxin, Calbiochem

• Synonyme(s) : MPTP Hydrochloride, Dopaminergic neurotoxin, MPTP
• Formule empirique (notation de Hill): C₁₂H₁₅N · xHCl
• Numéro CAS: 23007-85-4
• Poids moléculaire : 173.25 (free base basis)
• Numéro MDL: MFCD00012790
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: MPTP Hydrochloride,
• Pureté: ≥98% (TLC)
• Niveau de qualité: 100
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: white
• Solubilité: water: 100 mg/mL
• Température de stockage: 2-8°C
• InChI: 1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H
• Clé InChI: KOWJANGMTAZWDT-UHFFFAOYSA-N

Description

Description générale

A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.

Avertissement

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Langston, J. W., et al. 1985. Trends in Neurosci.8, 79.

Gabriel, T. L., et al. 1999. Nature Med.5, 1403.
Zhang, X., et al. 2010. J. Proteome Res.9, 1496.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H301 - H370
• Conseils de prudence: P260 - P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral - STOT SE 1
• Organes cibles: Nervous system
• Code de la classe de stockage: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3