56655

(−)-Methyl (R)-3-hydroxyvalerate

≥98.0% (sum of enantiomers, GC)

• Synonyme(s) : (−)-Methyl (R)-3-hydroxypentanoate
• Formule empirique (notation de Hill): C₆H₁₂O₃
• Numéro CAS: 60793-22-8
• Poids moléculaire : 132.16
• Numéro Beilstein : 4655380
• Numéro MDL: MFCD00077796
• Code UNSPSC : 12352108
• ID de substance PubChem : 57651591
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: ≥98.0% (sum of enantiomers, GC)
• Activité optique: [α]20/D −37±3°, c = 1% in chloroform
• Indice de réfraction: n20/D 1.427
• Point d'ébullition: 68-70 °C/5 mmHg (lit.)
• Densité: 1.029 g/mL at 20 °C (lit.)
• Chaîne SMILES: CC[C@@H](O)CC(=O)OC
• InChI: 1S/C6H12O3/c1-3-5(7)4-6(8)9-2/h5,7H,3-4H2,1-2H3/t5-/m1/s1
• Clé InChI: XHFXKKFVUDJSPJ-RXMQYKEDSA-N

Description

Application

• Preparation of single-enantiomer 2-methyl-4-heptanol, a pheromone of Metamasius hemipterus, using (S)-2-methoxy-2-(1-naphthyl)propionic acid.: This research outlines the synthesis of a single-enantiomer pheromone compound using (S)-2-methoxy-2-(1-naphthyl)propionic acid. The process highlights the importance of enantiopure intermediates like (−)-Methyl (R)-3-hydroxyvalerate in the synthesis of biologically active compounds (Ichikawa and Ono, 2006).

Autres remarques

Chiral building block for EPC syntheses; selective anti-alkylation of its dianion; OH protection and reduction of ester group to aldehyde or alcohol functions; stereoselective preparation of a dioxanone with pivalaldehyde

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 168.8 °F - closed cup
• Point d'éclair (°C): 76 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter