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V4512

Sigma-Aldrich

Vascular Endothelial Growth Factor from mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, powder, suitable for cell culture

Sinónimos:

mVEGF, VEGF

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10 μG
$496.000
50 μG
$1.110.000

$496.000

Fecha estimada de envío30 de abril de 2025

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10 μG
$496.000
50 μG
$1.110.000

About This Item

Número MDL:
MFCD01636149
Código UNSPSC:
12352202
NACRES:
NA.77

$496.000

Fecha estimada de envío30 de abril de 2025

Nombre del producto

Vascular Endothelial Growth Factor from mouse, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture

origen biológico

mouse

Nivel de calidad

100

recombinante

expressed in E. coli

Ensayo

≥98% (SDS-PAGE)

Formulario

powder

potencia

≤10 ng/mL

calidad

endotoxin tested

mol peso

protein 39 kDa

envase

pkg of 10 μg
pkg of 50 μg

condiciones de almacenamiento

avoid repeated freeze/thaw cycles

técnicas

cell culture | mammalian: suitable

impurezas

<1 EU/μg

Nº de acceso UniProt

Q00731

temp. de almacenamiento

−20°C

Información sobre el gen

mouse ... VEGFA(22339)

Descripción general

Vascular endothelial growth factor is also known as VPF, VEGF and MVCD1. It is secreted from endothelial cells and pericytes in response to hypoxia. It helps in inducing angiogenesis and microvascular hyperpermeability. VEGF levels are associated with vasculitic neuropathy and may be used to predict this disease.[1] It may also act as a marker in the development and progression of early precancerous lesions of oesophagus.[2]

Aplicación

Vascular endothelial growth factor (VEGF) supports development of new blood vessels during embryonic development and after vascular injury.Vascular endothelial growth factor from mouse was used for ELISA[3] and in matrigel plugs (matrigel was supplemented with VEGF).[4]

Otras notas

Homodimeric protein consisting of two 165 amino acid polypeptide chains of mouse VEGF.
2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Forma física

Lyophilized from a 0.2 μm filtered buffered solution.

Nota de análisis

The biological activity is measured by the ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells (HUVEC) and bovine aortic endothelial cells.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCW3097
MKCS8453
MKCQ7358
MKCP4955
MKCN4604

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Katsuhisa Tashiro et al.
Stem cells and development, 23(18), 2202-2210 (2013-12-19)
Vascular endothelial growth factor (VEGF) is reported to exhibit potent hematopoietic stem/progenitor cell (HSPC) mobilization activity. However, the detailed mechanisms of HSPC mobilization by VEGF have not been examined. In this study, we investigated the effect of VEGF on bone
Asieh Golozar et al.
European journal of cancer (Oxford, England : 1990), 50(16), 2855-2865 (2014-08-31)
Mechanisms involved in wound healing play some role in carcinogenesis in multiple organs, likely by creating a chronic inflammatory milieu. This study sought to assess the role of genetic markers in selected inflammation-related genes involved in wound healing (interleukin (IL)-1a
Victor Manolov et al.
Clinical laboratory, 60(9), 1573-1577 (2014-10-09)
Vascular endothelial growth factor (VEGF) is secreted from endothelial cells and pericytes in response to hypoxia. It induces angiogenesis and microvascular hyperpermeability. We observe serum VEGF concentrations in some patients with vasculitic neuropathy. Plasma VEGF was measured using GenWay's human
Benjamin B Bartelle et al.
Circulation research, 110(7), 938-947 (2012-03-01)
The formation and maintenance of a functional vasculature is essential for normal embryonic development, and genetic changes that affect the vasculature underlie pathogenesis in many human diseases. In vivo imaging in mouse models is required to understand the full complexity
Jafar Rezaie et al.
Journal of cellular biochemistry, 119(1), 524-535 (2017-06-14)
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level of Ang-1, Ang-2, cell migration, and trans-differentiation into pericytes and endothelial
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