This material is not reported as being light sensitive.
SML0443
SU-5402
≥98% (HPLC), powder, FGFR inhibitor
Sinónimos:
3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid, PF-02969207, PNU-0290908
Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
5 mg | Comprobar disponibilidad del carrito | $104.000 |
25 mg | Comprobar disponibilidad del carrito | $421.000 |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C17H16N2O3
Número CAS:
Peso molecular:
296.32
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleNombre del producto
SU-5402, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
light yellow to dark orange
solubility
DMSO: 10 mg/mL (clear solution)
storage temp.
−20°C
SMILES string
Cc1c[nH]c(\C=C2/C(=O)Nc3ccccc23)c1CCC(O)=O
InChI
1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
InChI key
JNDVEAXZWJIOKB-JYRVWZFOSA-N
Application
SU5402 has been used as a fibroblast growth factor receptor inhibitor:
- in cell signalling experiments to stimulate cells for MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
- to study its effect on the expression of osteogenic markers and expression of osteoprotegerin and RANKL (runt-related transcription factor(RUNX)-2
- to prepare a stock solution with DMSO (Dimethyl superoxide) for cell culture medium and also to co-treat embryos
- to study its effect on osteogenic markers.
Biochem/physiol Actions
SU-5402 is a FGFR antagonist and angiogenesis inhibitor.
SU-5402 is a FGFR antagonist; angiogenesis inhibitor.
SU-5402 has inhibitory effect on the action of tyrosine kinases. It competitively binds to the ATP-binding site on the fibroblast growth factor receptor (FGFR).
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
1 of 1
Este artículo | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 10 mg/mL (clear solution) | solubility DMSO: 20 mg/mL, clear (warmed), H2O: insoluble | solubility DMSO: 10 mg/mL, clear | solubility DMSO: 5 mg/mL (clear solution) |
| color light yellow to dark orange | color yellow to yellow-orange | color white to beige | color light orange to dark orange |
Still not finding the right product?
Explore all of our products under SU-5402
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
-
Is SU5402 SML0443 light sensetive?
1 answer-
Helpful?
-