SAB5701364

Anti-KRAS+HRAS+NRAS antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• species reactivity: mouse, rat, human
• concentration: 1.45 mg/mL
• technique(s): immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: P01111/P01112/P01116
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Descripción

General description

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide derived from human KRAS+HRAS+NRAS

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable