SAB5700609

Anti-FasLG antibody produced in rabbit

• Sinónimos: ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, FASLG, Fas ligand, FasL, FasLG, TNFSF6, TNLG1A
• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 14; 31
• reactividad de especies: human, mouse, rat
• concentración: 1.52 mg/ml
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: P48023
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FasLG(356)

Descripción

Descripción general

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Inmunógeno

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable