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RAB0298

Sigma-Aldrich

Human IL-4 ELISA Kit

for serum, plasma, cell culture supernatant and urine

Sinónimos:

B-cell stimulatory factor 1, BSF-1, IL-4, Interleukin-4

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 3.13-200 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL4(3565)

Categorías relacionadas

General description

The Human IL-4 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-4 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-4

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

IL-4 (Interleukin 4) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It exhibits anti-inflammatory responses and participates in immune processes by providing protection from intracellular pathogens. IL-4 also plays an important role in Th2 (T helper cells) differentiation. Additionally, it can suppress pro-inflammatory cytokines. IL-4 is associated with pemphigus. Also, mutation in the gene is linked with risk of dental implant loss. In children, IL-4 might be involved with risk of asthma and Mycoplasma pneumoniae infection.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Journal of cellular physiology, 237(1), 675-686 (2021-08-10)
Tendon and ligament (T/L) engineering strategies towards clinical practice have been challenged by a paucity of understanding in the identification and still poorly described characterization of cellular niches. Prospecting how resident cell populations behave in vitro, and how cryopreservation may
Association of interleukin 4 gene polymorphisms with dental implant loss.
Pigossi SC, et al.
Implant Dentistry, 23, 723-731 (2014)
Purification of a 130-kDa T cell glycoprotein that binds human interleukin 4 with high affinity.
Galizzi JP, et al.
The Journal of Biological Chemistry, 265, 439-444 (1990)
Interleukin 4 inhibition as a potential therapeutic in pemphigus.
Tavakolpour S and Tavakolpour V
Cytokine, 77, 189-195 (2016)
Associations of IL-2 and IL-4 Expression and Polymorphisms With the Risks of Mycoplasma pneumoniae Infection and Asthma in Children.
Wang RS
Archivos de bronconeumologia, 51, 571-578 (2015)
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