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P6126

(R)-(−)-Phenylephrine hydrochloride

≥99% (titration), powder, α₁-adrenoceptor agonist

Sinónimos:

(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

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Tamaño de envaseSKUDisponibilidadPrecio
10 g
Comprobar disponibilidad del carrito
$97.200
5 g
Comprobar disponibilidad del carrito
$106.000
25 g
Comprobar disponibilidad del carrito
$201.000
50 g
Comprobar disponibilidad del carrito
$316.000
100 g
Comprobar disponibilidad del carrito
$443.000

Acerca de este artículo

Fórmula lineal:
HOC6H4CH(CH2NHCH3)OH·HCl
Número CAS:
Peso molecular:
203.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-517-3
MDL number:
Beilstein/REAXYS Number:
4158948
Form:
powder

$97.200


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Nombre del producto

(R)-(−)-Phenylephrine hydrochloride, powder

form

powder

Quality Segment

mp

143-145 °C (lit.)

originator

Johnson & Johnson

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

General description

(R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug.

Application

(R)-(-)-Phenylephrine hydrochloride has been used:
  • in the preparation and culturing of cardiocytes and fibroblasts
  • to stimulate myocardial strips to measure slice contraction
  • in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo
  • to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes
  • to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality

Biochem/physiol Actions

α1-adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Este artículo
P81551533002P1250000
form

powder

form

powder

form

-

form

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

originator

Johnson & Johnson

originator

-

originator

-

originator

-

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1B

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Artículos

Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.






Número de artículo de comercio global

SKUGTIN
P6126-50G04061832092768
P6126-25G04061834392958
P6126-10G04061834392941
P6126-100G04061835253401
P6126-5G04061835253418

Questions

1–4 of 4 Questions  
  1. What are the recommended storage temperature and duration for the substance in solution?

    1 answer
    1. The stability of this product in solution has not been investigated, but is believed to be quite stable. The Certified Reference Material, product P-078, is a 1 mg/mL solution in methanol that is assigned a shelf life of approximately 5 years when stored frozen at ?20°C. Please see the link below to review a publication that reports aqueous solutions are stable for at least 66 days at room temperature.
      https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1986.tb00872.x

      Helpful?

  2. How to dissolve the power of PE.

    1 answer
    1. The product is tested for solubility at 50 mg/ml in water. This information can be found in the specification sheet or Certificate of Analysis accessible from the Product Detail Page.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. Is (R)-(-)-Phenylephrine hydrochloride the same as L-Phenylephrine hydrochloride?

    1 answer
    1. (R)-(-)-Phenylephrine hydrochloride is also named l-Phenylephrine hydrochloride (lower case el) or Levophenylephrine hydrochloride.

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