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N4382

Nalidixic acid sodium salt

DNA gyrase inhibitor, powder

1 of 1 reviewers received a sample product or took part in a promotion

Sinónimos:

1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt

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Talla/SKUDisponibilidadPrecio
1 g
Comprobar disponibilidad del carrito
$41.900
5 g
Comprobar disponibilidad del carrito
$131.000
25 g
Comprobar disponibilidad del carrito
$423.000
100 g
Comprobar disponibilidad del carrito
$635.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C12H11N2NaO3
Número CAS:
Peso molecular:
254.22
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
222-159-7
MDL number:
Beilstein/REAXYS Number:
3580062
Form:
powder

$41.900


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Nombre del producto

Nalidixic acid sodium salt, powder

Quality Segment

form

powder

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

DNA synthesis | interferes, enzyme | inhibits

originator

Sanofi Aventis

SMILES string

[Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12

InChI

1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1

InChI key

ROKRAUFZFDQWLE-UHFFFAOYSA-M

General description

Nalidixic acid is a quinolone and can block the activity of bacterial topoisomerase type II enzyme, thereby stopping bacterial replication. It is a potential antibacterial agent against Gram-negative bacteria than Gram-positive bacteria. Nalidixic acid has been studied in the management of urinary tract infections.
Chemical structure: quinolone

Application

Nalidixicacid has been used to treat the bacterial cultures to study itsresistance on Salmonella enterica and SalmonellaTyphimurium.

Biochem/physiol Actions

Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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description

powder

description

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description

815-950 μg/mg (Oxacillin)

description

β-lactamase inhibitor

form

powder

form

powder or crystals

form

powder

form

powder or crystals

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

originator

Sanofi Aventis

originator

-

originator

-

originator

-

mode of action

enzyme | inhibits, DNA synthesis | interferes

mode of action

DNA synthesis | interferes, enzyme | inhibits

mode of action

cell wall synthesis | interferes

mode of action

cell wall synthesis | interferes

antibiotic activity spectrum

Gram-positive bacteria, Gram-negative bacteria

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

Gram-positive bacteria, Gram-negative bacteria


pictograms

Health hazardExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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  1. United Kingdom
    • Review 1
    • Votes 0
    5 out of 5 stars.

    Good quality

    Very good quality for the price. Have been buying this product for years and have had no issues.

    Helpful?