MAK068
MPO Colorimetric Activity Assay Kit
sufficient for 100 colorimetric tests
Sinónimos:
Myeloperoxidase Colorimetric Activity Assay Kit
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About This Item
Código UNSPSC:
12161503
NACRES:
NA.84
Productos recomendados
uso
sufficient for 100 colorimetric tests
método de detección
colorimetric
enfermedades relevantes
cancer; cardiovascular diseases; hematological disorder
temp. de almacenamiento
−20°C
Información sobre el gen
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
Descripción general
Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.
Aplicación
MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.
Características y beneficios
Compatible with high-throughput handling systems.
Idoneidad
Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells
Principio
In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2
Código de clase de almacenamiento
10 - Combustible liquids
Punto de inflamabilidad (°F)
188.6 °F
Punto de inflamabilidad (°C)
87 °C
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