MAK058
D-Lactate Colorimetric Assay
sufficient for 100 colorimetric tests
Sinónimos:
D-Lactate Test Kit
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About This Item
Código UNSPSC:
12161503
NACRES:
NA.84
Productos recomendados
uso
sufficient for 100 colorimetric tests
aplicaciones
cosmetics
food and beverages
método de detección
colorimetric
enfermedades relevantes
neurological disorders; gastrointestinal diseases
temp. de almacenamiento
−20°C
Descripción general
D-Lactate, typically present in the bloodstream at nanomolar concentrations, is produced by an intestinal source or via the methylglyoxal pathway. In mammals, D-Lactate metabolism requires D-Lactate hydrogenase and is metabolized slowly, thus an increase in blood concentration levels can lead to acidemia and acidosis. The severity of this D-lactic acidosis can be associated with neurotoxic symptoms. Significant D-Lactate accumulations in the body can also be related to impaired metabolism and excretion.
Aplicación
D-Lactate Colorimetric Assay kit has been used to determine the stereospecificity of lactate produced.
Idoneidad
Suitable for use with samples of serum, plasma, cells, culture and fermentation media.
Principio
In this assay, D-Lactate is specifically oxidized by D-Lactate hydrogenase and generates a proportional colorimetric product measured at 450 nm. The useful concentration range in samples is 0.1-10 mM D-Lactate.
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Dam. 1 - Skin Corr. 1B
Código de clase de almacenamiento
8A - Combustible corrosive hazardous materials
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Poonam Naik et al.
Current eye research, 45(2), 184-189 (2019-08-31)
Purpose: Microbiological investigations of vitreous fluid have often failed to detect the causative agent in infectious endophthalmitis resulting in a clinical dilemma. D-Lactate is a byproduct of bacterial metabolism, and its accumulation in sterile body fluids indicates bacterial infection. The
William H. Hoffman et al.
Journal of clinical research in pediatric endocrinology, 12(2), 160-167 (2019-09-14)
To determine the time relationships of soluble receptor for glycation end-products (sRAGE), [a decoy of the advanced glycation end-products (AGE)-RAGE axis] and D-lactate, (a metabolite of methylglyoxal) in the inflammatory response to diabetic ketoacidosis (DKA). Sixteen children and adolescents with
Yanan Chen et al.
Journal of animal science and biotechnology, 12(1), 70-70 (2021-06-11)
Intestinal disorder is an important factor contributing to growth lag and high rates of morbidity and mortality of piglets with intrauterine growth retardation (IUGR). Resveratrol (RSV) and its derivative pterostilbene (PT) are natural stilbenes possessing various bioactivities, such as antioxidative
Ayca Erkin-Cakmak et al.
The Journal of clinical endocrinology and metabolism, 104(7), 3003-3011 (2019-03-15)
To investigate the link between dietary sugar consumption and two separate pathogenetic mechanisms associated with metabolic syndrome: de novo lipogenesis (DNL) and nonenzymatic glycation. We assessed changes in serum d-lactate (the detoxification end-product of methylglyoxal) concentration in response to 9
R Caputo Oliveira et al.
Journal of dairy science, 103(8), 7055-7067 (2020-06-15)
Our previously published paper demonstrated that fermented ammoniated condensed whey (FACW) supplementation improved feed efficiency and metabolic profile in postpartum dairy cows. The objective of this study was to further explore the effects of FACW supplementation on liver triglyceride content
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