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I6504

(−)-Isoproterenol hydrochloride

≥98% (TLC), powder, β-adrenoceptor agonist

Sinónimos:

(−)-Isoprenaline hydrochloride, (−)-N-Isopropyl-L-noradrenaline hydrochloride, (R)-3,4-Dihydroxy-α-(isopropylaminomethyl)benzyl alcohol hydrochloride

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Talla/SKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
$35.500
500 mg
Comprobar disponibilidad del carrito
$99.800
1 g
Comprobar disponibilidad del carrito
$136.000

Acerca de este artículo

Fórmula lineal:
3,4-(HO)2C6H3CH(OH)CH2NHCH(CH3)2·HCl
Número CAS:
Peso molecular:
247.72
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
6077193

$35.500


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Nombre del producto

(−)-Isoproterenol hydrochloride,

Quality Segment

mp

175 °C (dec.) (lit.)

solubility

soluble (50 mg/ml: H2O)

storage temp.

−20°C

SMILES string

Cl[H].CC(C)NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/t11-;/m0./s1

InChI key

IROWCYIEJAOFOW-MERQFXBCSA-N

Gene Information

human ... ADRB2(154)

Application

(−)-Isoproterenol hydrochloride has been used in in vitro explant culture. It has also been used in transcriptome analysis of heart.

Biochem/physiol Actions

Isoproterenol hydrochloride is useful in post transplantal organ recovery. It exhibits ionotropic and chronotropic effects. With respect to donor heart recovery, isoproterenol hydrochloride decreases peripheral and systemic vascular resistance. Isoproterenol also increases the heart rate.
β-adrenoceptor agonist; increases cytosolic cAMP.

Preparation Note

This material can be dissolved in 50 mg/ml of H2O.

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Este artículo
N5511PHL82241L9756
description

-

description

1.0 mg/mL, analytical standard, for drug analysis

description

phyproof® Reference Substance

description

≥99% (GC)

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

soluble (50 mg/ml: H2O)

solubility

-

solubility

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

mp

175 °C (dec.) (lit.)

mp

-

mp

-

mp

228-230 °C

Gene Information

human ... ADRB2(154)

Gene Information

human ... CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), CYP2A6(1548), KCNH1(3756)
mouse ... Chrna7(11441), Chrnb1(11443)
rat ... Chrna1(79557), Chrna2(170945), Chrna4(25590), Chrna7(25302), Chrnb2(54239), Chrnb4(25103)

Gene Information

-

Gene Information

-


Pictogramas

Exclamation mark

Palabra de advertencia

Warning

Códigos de peligro

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos diana

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–6 of 6 Questions  
  1. is product I65is product I6504 stable if reconstituted, aliquoted, and then frozen at -20C?

    1 answer
    1. The stock solutions may be stored at -20 degrees C in aliquots. Long-term stability studies have not been performed. However, information found in published literature indicates that it is quite stable. Please see the link below to review one example.
      https://pubmed.ncbi.nlm.nih.gov/18933/

      Helpful?

  2. Wie man das Produkt Isoproterenol-hydrochlorid #I6504 am besten? Und gibt es eine Konzentrationsangabe, bei der es sich am besten löst?

    1 answer
    1. To order this material, please navigate to the link https://www.sigmaaldrich.com/support/customer-support, click on "Pricing & Availability" under the Products Section with all the required information so that a member of the Customer Service team can reach out to assist further.

      This material can be dissolved in 50 mg/ml of H2O.

      Helpful?

  3. How should (-)-Isoproterenol hydrochloride, Product I6504, be stored?

    1 answer
    1. (-)-Isoproterenol hydrochloride is a powder that needs to be stored at -20°C.

      Helpful?

  4. What can be used to make a solution of (-)-Isoproterenol hydrochloride, Product I6504?

    1 answer
    1. We test the solubility of (-)-Isoproterenol hydrochloride in water at a concentration of 50 mg/mL. Isoproterenol hydrochloride is also soluble in ethanol at 20 mg/mL.

      Helpful?

  5. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  6. Can I use a brownish-pink solution of (-)-Isoproterenol hydrochloride, Product I6504?

    1 answer
    1. Aqueous solutions become pink to brownish-pink when exposed to air, and almost immediately so when made alkaline. This color change indicates degradation.

      Helpful?

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