H3128

Calconcarboxylic acid

suitable for use as an indicator for the titration of calcium

• Sinónimos: 2-Hydroxy-1-(2-hydroxy-4-sulfo-1-naphthylazo)-3-naphthoic acid, 3-Hydroxy-4-(2-hydroxy-4-sulfo-1-naphthylazo)naphthalene-2-carboxylic acid, Patton and Reeder’s reagent
• Fórmula empírica (notación de Hill): C₂₁H₁₄N₂O₇S
• Número CAS: 3737-95-9
• Peso molecular: 438.41
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24895550
• EC Number: 223-117-0
• Beilstein/REAXYS Number: 727492
• MDL number: MFCD00004078

Propiedades

• Quality Segment: 100
• form: powder
• mp: 300 °C
• solubility: 1 M NaOH: 10 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: OC(=O)c1cc2ccccc2c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c1O
• InChI: 1S/C21H14N2O7S/c24-16-10-17(31(28,29)30)13-7-3-4-8-14(13)18(16)22-23-19-12-6-2-1-5-11(12)9-15(20(19)25)21(26)27/h1-10,24-25H,(H,26,27)(H,28,29,30)/b23-22-
• InChI key: MVQBFZXBLLMXGS-FCQUAONHSA-N

Descripción

General description

Calconcarboxylic acid is a useful indicator for calcium titrations with EDTA in the presence of magnesium. It is also required for the staining of proteins in gels.

Calconcarboxylic acid is also known as Patton-Reeder indicator and is used in the determination of calcium at pH 12. Calconcarboxylic acid is a chelating agent and is used in the preparation of chelating sorbent along with chemically modified silica LiChroprep-NH₂, for trace metal analysis. Calconcarboxylic acid coupled with 3-aminopropyltriethoxysilane (APS-CCA), a fluorescent probe, facilitates the medical detection of Ca²⁺ ions in the blood with minimal blood backgrounds using hydrophobic hexadecyltrimethoxysilane (HDS) as substrate in fluorimetric microarray method.

Application

Calconcarboxylic acid (CCA) has been used in the preparation of poly-CCA film for leukemia diagnosis by immobilization, hybridization of DNA and detection by methylene blue and differential pulse voltammetry.

Analysis Note

Contains an inert diluent.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H315,H319,H335
• Indicaciones de precaución: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): dust mask type N95 (US), Eyeshields, Gloves