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D5817

DMXAA

≥98% (HPLC), solid, apoptosis inducer

Sinónimos:

5,6-Dimethylxanthenone-4-acetic Acid, ASA404, Vadimezan

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Talla/SKUDisponibilidadPrecio
5 mg
Comprobar disponibilidad del carrito
$213.000
25 mg
Comprobar disponibilidad del carrito
$730.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C17H14O4
Número CAS:
Peso molecular:
282.29
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$213.000


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Nombre del producto

DMXAA, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

color

light brown

solubility

DMSO: soluble >10 mg/mL

storage temp.

2-8°C

SMILES string

Cc1ccc2C(=O)c3cccc(CC(O)=O)c3Oc2c1C

InChI

1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)

InChI key

XGOYIMQSIKSOBS-UHFFFAOYSA-N

General description

5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a flavone acetic acid derivative. It acts as a vascular disrupting agent (VDA), which damages tumor vasculature and stimulates an anti-tumor immune response. It stimulates hemorrhagic necrosis.

Application

5,6-dimethylxanthenone-4-acetic acid (DMXAA) has been used to induce type-I IFN signaling in a stimulator of interferon genes (STING) dependent manner. It has also been used to study STING-dependent signaling in the absence of infection.

Biochem/physiol Actions

DMXAA is an apoptosis inducer; anti-vascular.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: soluble >10 mg/mL

solubility

DMSO: 10 mg/mL

solubility

DMSO: 100 mg/mL

solubility

H2O: 20 mg/mL, clear

color

light brown

color

light yellow

color

dark yellow

color

white to beige


signalword

Warning

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

pictograms

Exclamation mark

hcodes

Hazard Classifications

Acute Tox. 4 Oral



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