C4905

Galactocerebrosides from bovine brain

≥97% (TLC)

• Sinónimos: Ceramide β-D-galactoside
• Número CAS: 85305-88-0
• UNSPSC Code: 12352211
• NACRES: NA.77
• MDL number: MFCD00131116
• Assay: ≥97% (TLC)
• Form: powder

Propiedades

• Quality Segment: 200
• assay: ≥97% (TLC)
• form: powder
• storage temp.: −20°C

Descripción

General description

A mixture of type I (containing α-hydroxy fatty acid) and type II (containing non-hydroxy fatty acid) cerebrosides. Galactocerebroside (GalCer) is a glycosphingolipid, that consists of a single galactose residue, connected to ceramide . GalCer is present within the exofacial leaflet of the lipid bilayer.

Application

Galactocerebrosides from bovine brain has been used to find the receptor activity of surface-immobilized galactosylceramide. It has also been used in sulfatide binding assay.

Biochem/physiol Actions

Galactose linked to ceramide by a β-glycosidic linkage; the major lipid in adult brain, representing approximately 16% of total lipid; they are mainly localized to myelin and are markedly reduced in demyelinating diseases.

Galactocerebroside (GalCer) participates in the progression and maintenance of myelin. This oligodendroglial lipid is used as an immunohistochemical tool for studying oligodendrocytes.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)