Saltar al contenido
Merck

40733

Supelco

trans-2-Tetradecenoyl-L-carnitine

analytical standard

Sinónimos:

(2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-tetradecen-1-yl]oxy]-1-propanaminium inner salt, trans-2-Myristenoyl-L-carnitine, C14:1-Carnitine

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Fórmula empírica (notación de Hill):
C21H39NO4
Peso molecular:
369.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

assay

≥95.0% (LC/MS)

optical activity

[α]/D -12±2°, c = 0.1 in methanol

shelf life

limited shelf life, expiry date on the label

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

[O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O

General description

trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain β-oxidation defect in newborns.

Application

trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:
  • Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
  • Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry
Yoon R-H, et al.
Annals of pediatric endocrinology & metabolism, 20(3), 119-119 (2015)
Tandem mass spectrometry screening for very long-chain acyl-CoA dehydrogenase deficiency: the value of second-tier enzyme testing
Spiekerkoetter U, et al.
The Journal of Pediatrics, 157(4), 668-673 (2010)
Quantification of metabolites in dried blood spots by direct infusion high resolution mass spectrometry
Van der Ham M, et al., et al.
Analytica Chimica Acta, 979, 45-50 (2017)
Differences between acylcarnitine profiles in plasma and bloodspots
Diekman FE, et al.
Molecular Genetics and Metabolism, 110(1-2), 116-121 (2013)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico