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165304

D-(–)-2-Amino-5-phosphonopentanoic Acid

≥97% (HPLC), solid, NMDA receptor antagonist, Calbiochem®

Sinónimos:

D-(–)-2-Amino-5-phosphonopentanoic Acid, D-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate

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Fórmula empírica (notación de Hill):
C5H12NO5P
Número CAS:
Peso molecular:
197.13
UNSPSC Code:
12352106
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
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Nombre del producto

D-(–)-2-Amino-5-phosphonopentanoic Acid, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

Quality Segment

assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

white

solubility

dilute aqueous base: 1 mg/mL, water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[P](=O)([O-])([O-])CCC[C@@H]([N+H3])C(=O)[O-]

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1

InChI key

VOROEQBFPPIACJ-SCSAIBSYSA-L

General description

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.

Biochem/physiol Actions

Cell permeable: no
Primary Target
NMDA receptor antagonist
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
Schulte, M.K., et al. 1994. Brain Res. 649, 203.
Davis, S., et al. 1992. J. Neurosci. 12, 21.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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Este artículo
A8054324900489350
description

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

description

NMDA receptor antagonist

description

α,β-Adrenergic receptor agonist.

description

α,β-Adrenergic agonist.

form

solid

form

powder

form

solid

form

crystalline solid

assay

≥97% (HPLC)

assay

≥98% (TLC)

assay

≥95% (TLC)

assay

≥97% (LC/MS)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated (hygroscopic), OK to freeze, protect from light

storage condition

-

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

desiccated, OK to freeze


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Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable



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