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1.06370

Sodium dihydrogen phosphate

anhydrous 99.99 Suprapur®

Sinónimos:

Sodium dihydrogen phosphate, Sodium biphosphate

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Fórmula empírica (notación de Hill):
H2NaO4P
Número CAS:
Peso molecular:
119.98
UNSPSC Code:
12352302
EC Index Number:
231-449-2
NACRES:
NA.21
MDL number:
Assay:
99.99%
Form:
crystals
Solubility:
850 g/L
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Quality Segment

description

for inorganic trace analysis

assay

99.99%

form

crystals

potency

8290 mg/kg LD50, oral (Rat), >7940 mg/kg LD50, skin (Rabbit)

technique(s)

AAS: suitable

pH

4.5 (20 °C, 10 g/L in H2O)

mp

>450 °C ((> 842 °F))

solubility

850 g/L

bulk density

940 kg/m3

anion traces

chloride (Cl-): ≤5 ppm, sulfate (SO42-): ≤30 ppm

cation traces

As: ≤0.05 ppm, Ba: ≤10.0 ppm, Ca: ≤0.50 ppm, Cd: ≤0.010 ppm, Ce: ≤0.010 ppm, Co: ≤0.010 ppm, Cs: ≤5 ppm, Cu: ≤0.010 ppm, Eu: ≤0.010 ppm, Fe: ≤0.05 ppm, Hg: ≤0.05 ppm, K: ≤5.0 ppm, La: ≤0.010 ppm, Li: ≤1.0 ppm, Mg: ≤0.50 ppm, Mn: ≤0.010 ppm, N: ≤10 ppm, Ni: ≤0.010 ppm, Pb: ≤0.010 ppm, Rb: ≤5.0 ppm, Sm: ≤0.010 ppm, Sr: ≤0.50 ppm, Tl: ≤0.01 ppm, Y: ≤0.010 ppm, Yb: ≤0.010 ppm, Zn: ≤0.010 ppm

storage temp.

2-30°C

SMILES string

[Na+].[P](=O)([O-])([O-])[O-].[H+].[H+]

InChI

1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

AJPJDKMHJJGVTQ-UHFFFAOYSA-M

Application


  • Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the creation of a multiparticulate drug delivery system using sodium dihydrogen phosphate to induce in situ amorphisation, enhancing the bioavailability of poorly water-soluble drugs (Holm et al., 2022).

Analysis Note

Purity (metallic): ≥ 99.99 %
Assay (acidimetric): ≥ 99.0 %
Spec. Absorbance A at 260 nm (2 cm; 10 %): ≤ 0.020
Chloride (Cl): ≤ 5 ppm
Sulfate (SO₄): ≤ 30 ppm
Total nitrogen (N): ≤ 10 ppm
As (Arsenic): ≤ 0.05 ppm
Ba (Barium): ≤ 10.0 ppm
Ca (Calcium): ≤ 0.50 ppm
Cd (Cadmium): ≤ 0.010 ppm
Ce (Cerium): ≤ 0.010 ppm
Co (Cobalt): ≤ 0.010 ppm
Cs (Cesium): ≤ 5 ppm
Cu (Copper): ≤ 0.010 ppm
Eu (Europium): ≤ 0.010 ppm
Fe (Iron): ≤ 0.05 ppm
Hg (Mercury): ≤ 0.05 ppm
K (Potassium): ≤ 5.0 ppm
La (Lanthanum): ≤ 0.010 ppm
Li (Lithium): ≤ 1.0 ppm
Mg (Magnesium): ≤ 0.50 ppm
Mn (Manganese): ≤ 0.010 ppm
Ni (Nickel): ≤ 0.010 ppm
Pb (Lead): ≤ 0.010 ppm
Rb (Rubidium): ≤ 5.0 ppm
Sm (Samarium): ≤ 0.010 ppm
Sr (Strontium): ≤ 0.50 ppm
Tl (Thallium): ≤ 0.01 ppm
Y (Yttrium): ≤ 0.010 ppm
Yb (Ytterbium): ≤ 0.010 ppm
Zn (Zinc): ≤ 0.010 ppm

Legal Information

SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany


Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

Clase de almacenamiento

11 - Combustible Solids



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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