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Key Documents

06-807

Sigma-Aldrich

Anti-LAT Antibody

Upstate®, from rabbit

Sinónimos:

Anti-IMD52, Anti-pp36

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... LAT(27040)
mouse ... Lat(16797)

Specificity

Recognizes both forms of LAT.

Immunogen

GST-tagged fusion protein corresponding to residues 31-233 of human LAT

Application

Anti-LAT Antibody detects level of LAT & has been published & validated for use in IP & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

Quality

routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

Target description

36/38 kDa

Physical form

Format: Purified
Protein A Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide.
Protein A purified

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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T Harder et al.
The Journal of cell biology, 151(2), 199-208 (2000-10-19)
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Clark, JM; Annenkov, AE; Panesar, M; Isomaki, P; Chernajovsky, Y; Cope, AP
Proceedings of the National Academy of Sciences of the USA null
Elisabeth Sarri et al.
The Biochemical journal, 369(Pt 2), 319-329 (2002-10-11)
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Rush desensitization (DS) is a widely used and effective clinical strategy for the rapid inhibition of IgE-mediated anaphylactic responses. However, the cellular targets and underlying mechanisms behind this process remain unclear. Recent studies have implicated mast cells (MCs) as the

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