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Merck

O-901

Supelco

Oxazepam-d5 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C15D5H6ClN2O2
Número de CAS:
Peso molecular:
291.74
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

shipped in

wet ice

storage temp.

−20°C

SMILES string

[2H]c1c([2H])c([2H])c(c([2H])c1[2H])C2=NC(O)C(=O)Nc3ccc(Cl)cc23

InChI

1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)/i1D,2D,3D,4D,5D

InChI key

ADIMAYPTOBDMTL-RALIUCGRSA-N

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General description

Oxazepam is a benzodiazepine drug used to treat anxiety and insomnia and to control the symptoms of alcohol withdrawal. This stable-labeled internal standard is suitable for isotope dilution methods or the quantitation of oxazepam levels using GC/MS or LC/MS in testing applications such as clinical toxicology, urine drug testing, forensic analysis or pain prescription monitoring.

Application

  • Application as an internal standard: Oxazepam-d5 serves as an internal standard for the gas chromatography-mass spectrometry analysis of benzodiazepines, enhancing accuracy and precision in quantifying drugs like lorazepam in biological samples (Pichini et al., 1999).
  • Quantification of benzodiazepine metabolites: Utilized in the sensitive detection and quantification of flunitrazepam metabolites in urine, demonstrating its role in forensic toxicology to identify drug use patterns (elSohly et al., 1997).
  • Enhancement of mass spectrometry methodologies: Oxazepam-d5 aids in improving the methods of mass spectrometry by serving as a standard reference material, crucial for the precise measurement of benzodiazepine metabolites (Meatherall, 1994).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Bernhard Watzer et al.
International journal of legal medicine, 129(4), 759-769 (2014-12-20)
Arthrotec(®) (AT) is a combination of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and misoprostol (MP), a synthetic analogue of prostaglandin E1 (PGE1). MP is a lipophilic methyl ester prodrug. It is readily metabolized to the biologically active misoprostol acid (MPA).
André Valle de Bairros et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 975, 24-33 (2014-12-03)
In this study, it is shown a method for the determination of benzodiazepines and their main metabolites in urine samples by hollow-fiber liquid-phase microextraction (LPME) in the three-phase mode. Initially, the hydrolysis step was performed using 100 μL of sodium
Niclas Stephanson et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 189-196 (2015-02-18)
A mass spectrometric method for drugs of abuse testing in exhaled breath employing a sampling device collecting aerosol particles was developed and applied in routine use. Analytes covered were amphetamine, methamphetamine, 6-acetylmorphine, morphine, cocaine, benzoylecgonine, diazepam, oxazepam and tetrahydrocannabinol. The

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