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Merck

857503P

Avanti

16:0-a15:0 PC

Avanti Research - A Croda Brand (857503P), powder

Sinónimos:

1-Palmitoyl-(12S-methylmyristoyl)-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C39H78NO8P
Número de CAS:
Peso molecular:
720.01
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (857503P-10MG)
pkg of 1 × 5 mg (857503P-5MG)

manufacturer/tradename

Avanti Research - A Croda Brand (857503P)

lipid type

phospholipids
bacterial lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCC[C@H](C)CC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

General description

Phosphatidylcholine (PC) is one of the major zwitterionic glycerophospholipids of the eukaryotic membranes. PC is synthesized in higher eukaryotes by triple methylation of phosphatidylethanolamine and by the cytidine diphosphate (CDP)-choline pathway. PC is a cylindrical shaped molecule.

Biochem/physiol Actions

Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. Biosynthesis of PC is essential for normal very low density lipoprotein secretion from hepatocytes. PC is the dominant phospholipid present in cancer and non-neoplastic tissues.

Packaging

5 mL Amber Glass Screw Cap Vial (857503P-5MG and 857503P-10MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Thematic review series: glycerolipids. Phosphatidylcholine and choline homeostasis
Li Z and Vance DE
Journal of Lipid Research, 49(6), 1187-1194 (2008)
Nobuya Kurabe et al.
Cancer science, 104(10), 1295-1302 (2013-07-03)
The identification of cancer biomarkers is critical for target-linked cancer therapy. The overall level of phosphatidylcholine (PC) is elevated in colorectal cancer (CRC). To investigate which species of PC is overexpressed in colorectal cancer, an imaging mass spectrometry was performed
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)

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