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Merck

840060P

Avanti

16:0-18:2 PS

1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Sinónimos:

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(16:0/18:2(9Z,12Z))

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About This Item

Fórmula empírica (notación de Hill):
C40H73NO10PNa
Número de CAS:
Peso molecular:
781.97
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840060P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 840060P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H74NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,36-37H,3-10,12,14-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b13-11-,18-17-;/t36-,37+;/m1./s1

InChI key

WPLLCKLCLMRAPV-WHVRKWPVSA-M

Categorías relacionadas

General description

Phosphatidylserine (PS) is an acidic phospholipid, abundantly found in the protein myelin. It is localized to the membranes and present in plasma. PS constitutes 2% to 20% of the total phospholipid mass.

Application

16:0-18:2 PS or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt) might be used in the preparation of giant unilamellar liposomes (GULs).

Biochem/physiol Actions

Phosphatidylserine (PS) supports nerve cell membranes and myelin. It affects the catabolism and anabolism of neurotransmitters acetylcholine (ACh), norepinephrine, serotonin and dopamine.

Packaging

5 mL Clear Glass Sealed Ampule (840060P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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A Y Dunina-Barkovskaya et al.
The Journal of membrane biology, 198(2), 77-87 (2004-05-13)
Low gadolinium concentrations induce rapid gigaseal formation and cell adhesion to glass and plastic (polystyrene) substrates in the slime mutant of Neurospora crassa. Cellular adhesion is independent of an integrin-mediated mechanism, because pretreatment with the oligopeptide ARG-GLY-ASP-SER (RGDS) did not
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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