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810131C

Avanti

16:0-12:0 NBD PC

Avanti Research - A Croda Brand 810131C

Sinónimos:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C42H74N5O11P
Número de CAS:
Peso molecular:
856.04
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810131C-1mg)
pkg of 5 × 1 mL (810131C-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810131C

concentration

1 mg/mL (810131C-1mg)
1 mg/mL (810131C-5mg)

shipped in

dry ice

storage temp.

−20°C

Categorías relacionadas

General description

Phosphatidylcholine (PC) is a common phospholipid found in eukaryotes and a prime metabolite of glycerolipid metabolism. It is a vital component of the mucosal layer of the colon. NBD PC is a fluorescently labeled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to phosphatidylcholine.

Application

16:0-12:0 NBD PC has been used as a fluorescent marker to study the adsorption of hyaluronan (HA) onto a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayer deposited on a silica surface by fluorescent microscopy. It may also be used:
  • in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes
  • as a fluorophore for DPPC in fluorescence recovery experiments
  • as a substrate to test scramblase activity

Biochem/physiol Actions

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is useful in the study of cellular processes as it functions as a fluorescent analog in lipid membranes and phospholipid phase transitions.

Packaging

5 mL Amber Glass Screw Cap Vial (810131C-1mg)
5 mL Amber Glass Screw Cap Vial (810131C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3


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The diffusion law of DMPC and DPPC in Supported Lipid Bilayers (SLB), on different substrates, has been investigated in details by Fluorescence Recovery After Patterned Photobleaching (FRAPP). Over micrometer length scales, we demonstrate the validity of a purely Brownian diffusive
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