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Key Documents

810120P

Avanti

18:0 PEG2000 PE CF

Avanti Research - A Croda Brand

Sinónimos:

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (ammonium salt)

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About This Item

Número de CAS:
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

packaging

pkg of 1 × 1 mg (810120P-1mg)
pkg of 1 × 500 μg (810120P-500ug)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) lipid comprises hydrophilic polyethylene glycol (PEG) polymer in its head groups. DSPE-PEG(2000) micelles exist as spheroid in aqueous solution.

Application

18:0 PEG2000 PE CF may be used:
  • in in vitro release assays from nanoemulsion (NE)
  • for the labeling PEGylated LPD (liposome-polycation-DNA) for size exclusion chromatography studies
  • as a fluorescent probe to monitor shape transformation in giant vesicles

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) micelles aid in nanoparticles based drug delivery. It has potential to solubilize hydrophobic drugs and aid in the controlled release of drugs. 18:0 PEG2000 PE CF also called the DSPE−PEG2000, prevents the uptake of drugs by mononuclear phagocyte system and is a potential drug carrier for cancer therapy.

Packaging

5 mL Clear Glass Sealed Ampule (810120P-1mg)
5 mL Clear Glass Sealed Ampule (810120P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Shape Transformations of Lipid Vesicles by Insertion of Bulky-Head Lipids
Tsuda S, et al.
PLoS ONE, 10(7), e0132963-e0132963 (2015)
Nanoparticles evading the reticuloendothelial system: role of the supported bilayer
Li SD and Huang L
Biochimica et Biophysica Acta - Biomembranes, 1788(10), 2259-2266 (2009)
Morphology and physical properties of hydrophilic-polymer-modified lipids in supported lipid bilayers
Kakimoto Y, et al.
Langmuir, 34(24), 7201-7209 (2018)
Repeated injections of PEG-PE liposomes generate anti-PEG antibodies
Sroda K, et al.
Cellular & Molecular Biology Letters, 10, 37-47 (2005)
Molecular-matched materials for anticancer drug delivery and imaging
Wang D, et al.
Nanomedicine : nanotechnology, biology, and medicine, 10(19), 3003-3013 (2015)

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