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Documentos clave

800811O

Avanti

18:1 DG

Avanti Research - A Croda Brand

Sinónimos:

1-2-di-(9Z-octadecenoyl)-sn-glycerol; DG(18:1(9Z)/18:1(9Z)/0:0); DOG

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About This Item

Fórmula empírica (notación de Hill):
C39H72O5
Número de CAS:
Peso molecular:
620.99
Número MDL:
Código UNSPSC:
12352211
NACRES:
NA.25

descripción

1-2-dioleoyl-sn-glycerol, neat oil

Ensayo

>99% (TLC)

Formulario

liquid

envase

pkg of 1 × 10 mg (with screw cap (800811O-10mg))
pkg of 2 × 100 mg (with screw cap (800811O-200mg))
pkg of 5 × 100 mg (with screw cap 800811O-500mg)
pkg of 1 × 25 mg (with screw cap (800811O-25mg))

fabricante / nombre comercial

Avanti Research - A Croda Brand

tipo de lípido

neutral glycerides
neutral lipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

O([C@H](COC(=O)CCCCCCC\C=C\CCCCCCCC)CO)C(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3/b19-17+,20-18-/t37-/m0/s1

Clave InChI

AFSHUZFNMVJNKX-CSWDEDFYSA-N

Categorías relacionadas

Descripción general

Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage.

Aplicación

18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant protein His-AtROP6.

Envase

5 mL PTFE Vial with Screw Cap (800811O-10mg)
5 mL PTFE Vial with Screw Cap (800811O-200mg)
5 mL PTFE Vial with Screw Cap (800811O-25mg)
5 mL PTFE Vial with Screw Cap (800811O-500mg)

Almacenamiento y estabilidad

Diacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.

Otras notas

Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Effective concentration:
Most biological responses saturate at 20 to 250 μM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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