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W530098

Sigma-Aldrich

Naringenin

natural (US), 98%

Sinónimos:

(±)-Naringenin, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyflavanone

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About This Item

Fórmula empírica (notación de Hill):
C15H12O5
Número de CAS:
67604-48-2
Peso molecular:
272.25
FEMA Number:
4797
EC Number:
266-769-1
MDL number:
MFCD00006844
UNSPSC Code:
12164502
PubChem Substance ID:
329830749
NACRES:
NA.21

biological source

Citrus paradisi Macf.

grade

natural (US)

assay

98%

mp

247-250 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

SMILES string

OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O

InChI

1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChI key

FTVWIRXFELQLPI-UHFFFAOYSA-N

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General description

Naringenin is a bioactive flavonoid found in citrus and grapefruit.

Application

Naringenin has been used in a study to compare its antigenotoxic and antioxidative activity with that of naringenin-oxime.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Naringin analytical standard

Supelco

91842

Naringin

Hesperetin analytical standard

Supelco

H4125

Hesperetin

Hesperidin ≥80% (HPLC)

Sigma-Aldrich

H5254

Hesperidin

Apigenin ≥97% (TLC), from citrus

Sigma-Aldrich

SMB00702

Apigenin

Tangeretin ≥95% (HPLC)

Sigma-Aldrich

T8951

Tangeretin

Narirutin phyproof® Reference Substance

PHL83339

Narirutin

Xingyuan Shi et al.
Journal of cellular and molecular medicine, 25(5), 2563-2571 (2021-02-02)
Lung cancer is one of the major cause for high-death rate all over the world, due to increased metastasize and difficulties in diagnosis. Naringenin is naturally occurring flavonoid found in various fruits including tomatoes, citrus fruit and figs. Naringenin is
Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells
Kocyigit A, et al
Drug and Chemical Toxicology, 39(1), 66-73 (2016)
Ruibing Chen et al.
Frontiers in plant science, 9, 789-789 (2018-07-18)
Scutellarin, a flavonoid 7-O-glucuronide, is an essential bioactive compound of Erigeron breviscapus (Vaniot) Hand.-Mazz. used for the treatment of cerebrovascular diseases. However, due to overexploitation and overuse, E. breviscapus is facing the problems of extinction and habitat degradation. In this
Nada Oršolić et al.
European journal of nutrition, 53(5), 1217-1227 (2013-11-26)
Reactive oxygen species play a role in a number of degenerative conditions including osteoporosis. Flavonoids as phyto-oestrogens exert physiological effects against oxidative stress diseases. We developed a retinoic acid-induced bone loss model of rats to assess whether flavonoids and alendronate
Barbara Napoli et al.
Frontiers in neuroscience, 13, 1202-1202 (2019-12-06)
Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominant
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