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Merck

289647

Sigma-Aldrich

3-Amino-4-hydroxybenzoic acid

97%, for peptide synthesis

Sinónimos:

4-Hydroxy-3-aminobenzoic acid

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About This Item

Fórmula lineal:
H2NC6H3(OH)CO2H
Número de CAS:
Peso molecular:
153.14
Beilstein/REAXYS Number:
972238
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

product name

3-Amino-4-hydroxybenzoic acid, 97%

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

208 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1cc(ccc1O)C(O)=O

InChI

1S/C7H7NO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,8H2,(H,10,11)

InChI key

MRBKRZAPGUCWOS-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Hirokazu Suzuki et al.
Journal of bacteriology, 189(5), 2155-2159 (2006-12-13)
An arylamine N-acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct from other eukaryotic and bacterial NATs in that it acetylated various 2-aminophenol derivatives more effectively than
Hirokazu Suzuki et al.
The Journal of antibiotics, 60(6), 380-387 (2007-07-10)
In grixazone biosynthesis by Streptomyces griseus, a key intermediate 3-amino-4-hydroxybenzoic acid (3,4-AHBA) is converted to another key intermediate 3-amino-4-hydroxybenzaldehyde (3,4-AHBAL). Two genes griC and griD in the grixazone biosynthesis gene cluster were found to be responsible for this conversion, because
Hirokazu Suzuki et al.
The Journal of biological chemistry, 281(48), 36944-36951 (2006-09-28)
The shikimate pathway, including seven enzymatic steps for production of chorismate via shikimate from phosphoenolpyruvate and erythrose-4-phosphate, is common in various organisms for the biosynthesis of not only aromatic amino acids but also most biogenic benzene derivatives. 3-Amino-4-hydroxybenzoic acid (3,4-AHBA)
Christian Gerecke et al.
Epigenetics, 15(3), 307-322 (2019-09-12)
Mutations in the enzyme isocitrate dehydrogenase 1 (IDH1) lead to metabolic alterations and a sustained formation of 2-hydroxyglutarate (2-HG). 2-HG is an oncometabolite as it inhibits the activity of α-ketoglutarate-dependent dioxygenases such as ten-eleven translocation (TET) enzymes. Inhibitors of mutant
Experience with cheetan in management of HIV infection.
J Chege et al.
East African medical journal, 74(7), 460-461 (1997-07-01)

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