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D7441

Daltroban

>98% (HPLC)

Synonym(s):

4-[2-[(4-Chlorophenylsulfonyl)amino]ethyl]benzeneacetic acid, BM-13505, SKF-96148

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5 mg
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R$ 1.669,00

About This Item

Empirical Formula (Hill Notation):
C16H16ClNO4S
CAS Number:
79094-20-5
Molecular Weight:
353.82
NACRES:
NA.77
PubChem Substance ID:
24724468
UNSPSC Code:
12352200
MDL number:
MFCD00868295
Assay:
>98% (HPLC)
Form:
solid
Quality level:
100

R$ 1.669,00

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Quality Level

100

assay

>98% (HPLC)

form

solid

color

white

mp

132.5-137.4 °C (lit.)

solubility

DMSO: soluble 22 mg/mL

SMILES string

OC(=O)Cc1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1

InChI

1S/C16H16ClNO4S/c17-14-5-7-15(8-6-14)23(21,22)18-10-9-12-1-3-13(4-2-12)11-16(19)20/h1-8,18H,9-11H2,(H,19,20)

InChI key

IULOBWFWYDMECP-UHFFFAOYSA-N

Gene Information

human ... TBXA2R(6915)

General description

Exerts protective effects on brain infarction, heart cell injury due to hypoxia and hypoglycemia and lowers serum CPK activity.

Biochem/physiol Actions

Selective thromboxane A2 receptor antagonist

Features and Benefits

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
C3993P5624324412
Daltroban >98% (HPLC)

Sigma-Aldrich

D7441

Daltroban

Carvedilol ≥98% (HPLC), solid

Sigma-Aldrich

C3993

Carvedilol

PD-118057 ≥98% (HPLC), solid

Sigma-Aldrich

P5624

PD-118057

Dynamin Inhibitor III, Phthaladyn-23

Sigma-Aldrich

324412

Dynamin Inhibitor III, Phthaladyn-23

form

solid

form

solid

form

solid

form

solid

assay

>98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMSO: soluble 22 mg/mL

solubility

DMSO: >20 mg/mL

solubility

DMSO: 9 mg/mL

solubility

DMSO: 7 mg/mL

color

white

color

white to off-white

color

light yellow

color

light yellow to beige

mp

132.5-137.4 °C (lit.)

mp

-

mp

-

mp

-

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
063K4608

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A Rizzo et al.
The American journal of physiology, 268(5 Pt 2), H1954-H1958 (1995-05-01)
The effects of platelet-activating factor (PAF) on vascular resistance and capillary permeability were studied in the isolated rat hindquarter. Six groups were studied (n = 30): control; PAF alone (1.4 microM); and PAF (1.4 microM) pretreated with ibuprofen (30 mg/kg)
F Bertolino et al.
Naunyn-Schmiedeberg's archives of pharmacology, 356(4), 462-466 (1998-01-24)
We sought to determine whether the intrinsic pulmonary hypertensive activity of the purported thromboxane A2/prostanoid (TP) receptor antagonist, daltroban, was mediated by TP receptors, using the high efficacy TP receptor agonist, U-46619, and the silent TP receptor antagonist, SQ 29,548.
Sabine Pestel et al.
Laboratory investigation; a journal of technical methods and pathology, 83(12), 1733-1741 (2003-12-24)
Various inflammatory stimuli such as anaphylatoxin C5a, zymosan, and lipopolysaccharides (LPSs) have been reported both to enhance glucose output in the perfused rat liver and to induce prostanoid (ie, prostaglandin and thromboxane) release from Kupffer cells, the resident liver macrophages.
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Global Trade Item Number

SKUGTIN
D7441-25MG04061832270463
D7441-5MG04061832785332

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