1271008

Floxuridine

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 5-Fluoro-2′-deoxyuridine, 2′-Deoxy-5-fluorouridine, FUDR, Floxuridine
• Formula empirica (notazione di Hill): C₉H₁₁FN₂O₅
• Numero CAS: 50-91-9
• Peso molecolare: 246.19
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749849
• MDL number: MFCD00006530
• Beilstein/REAXYS Number: 90221

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• API family: floxuridine
• manufacturer/tradename: USP
• mp: 148 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• InChI key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
• Gene Information: human ... TYMS(7298)

Descrizione

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Floxuridine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Floxuridine for Injection

Biochem/physiol Actions

Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable