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1011029

USP

Acitretin Related Compound B

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

Ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate, Etretinate

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About This Item

Formula empirica (notazione di Hill):
C23H30O3
Numero CAS:
54350-48-0
Peso molecolare:
354.48
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

acitretin

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

InChI

1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+
HQMNCQVAMBCHCO-DJRRULDNSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Acitretin Related Compound B USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Acitretin

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Avvertenze

Danger

Indicazioni di pericolo

H315,H335,H360D,H410

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Shigeyoshi Tsuji et al.
Clinical orthopaedics and related research, 468(4), 1173-1177 (2009-08-07)
Abnormal reactions accompanied by bone formation in the osteoarticular region induced by long-term administration of etretinate have been reported. We treated a patient who received continuous treatment of psoriatic erythroderma with etretinate for 7 years, and who had an osseous
H-D Park et al.
International journal of clinical pharmacology and therapeutics, 47(7), 476-482 (2009-07-31)
Acitretin is used for the treatment of psoriasis. The purpose of this study was to validate an HPLC method for the determination of acitretin and etretinate and to investigate the pharmacokinetic characteristics of acitretin in healthy Korean subjects. Plasma samples
Emiko Akasaka et al.
The Journal of dermatology, 40(4), 238-243 (2013-01-22)
Various therapies have been tried for psoriasis. In Japan, biologics began to be used for psoriasis treatment in January 2010. Their clinical efficacy is well known, but biologics cannot be used in all psoriasis patients for reasons such as side-effects
Hyung-Doo Park et al.
Transfusion, 48(11), 2395-2400 (2008-07-29)
Acitretin and etretinate are potentially teratogenic. Many people taking acitretin for psoriasis have donated blood during the deferral period in Korea. Therefore, many of the blood products from these donors treated with acitretin have been circulated in Korea. A high-performance
Photoleukomelanoderma possibly caused by etretinate in a patient with psoriasis.
Mariko Seishima et al.
Acta dermato-venereologica, 90(1), 85-86 (2010-01-29)
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