821834

TOYOPEARL GigaCap^® S-650M Bulk Media

phase sulphonyl, bottle of 250 mL, 75 μm particle size

• Sinonimo/i: TOYOPEARL GigaCap^® S-650 Cation Exchange Media
• Codice UNSPSC: 41115700

Proprietà

• Nome Commerciale: TOYOPEARL^®
• Forma fisica: slurry
• Caratteristiche: counter ion Na+
• Confezionamento: bottle of 250 mL
• Produttore/marchio commerciale: Tosoh 21834
• Parametri: 3 bar max. pressure
• tecniche: LPLC: suitable
• Matrice: hydroxylated methacrylic polymer
• Gruppo funzionale matrice: sulphonyl phase
• Dimensione particelle: 75 μm
• pH di lavoro: 3-13
• Capacità: 156 g/L±20 adsorption capacity (hIgG)
• Tecnica di separazione: cation exchange

Descrizione

Descrizione generale

Toyopearl GigaCap S-650 resin is a high capacity, high resolution cation exchange resin* optimized for process scale applications, including the capture and purification of IgG as well as the polishing of monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of cationic binding sites for increased resin capacity.
While Toyopearl GigaCap S-650M resin was specifically optimized for IgG, with dynamic binding capacities in the vicinity of 140 mg/mL for IgG, it also exhibits high binding capacities for smaller proteins. Typical dynamic binding capacities for lysozyme are in excess of 160 mg/mL.
Toyopearl GigaCap S-650S resin has dynamic binding capacities approaching 165 g/L for gamma globulin. This high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap S-650S ideal for high resolution applications.
Toyopearl GigaCap S-650 resin is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of Toyopearl GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap S-650M resin also has excellent base stability in 1.0 mol/L NaOH and shows robust clean in place (CIP) properties with minimal loss of capacity after 50 X 1 hour cycles of caustic exposure also using 1.0 mol/L NaOH. (data)
*specifically designed for packed bed use

Specifiche

Clean in place with 0.5 M NaOH or 0.1 M HCl.

Stato fisico

72% (v/v) slurry in 20% (v/v) ethanol

Shipped in 20% (v/v) ethanol.

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Note legali

Toyopearl is a registered trademark of Tosoh Corporation

Toyopearl GigaCap is a registered trademark of Tosoh Corporation

Informazioni sulla sicurezza

• Pittogrammi: GHS02
• Avvertenze: Warning
• Indicazioni di pericolo: H226
• Consigli di prudenza: P210 - P233 - P240 - P241 - P242 - P243
• Classi di pericolo: Flam. Liq. 3
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 104.0 °F - closed cup
• Punto d’infiammabilità (°C): 40 °C - closed cup