This product has not been analyzed for stability with repetitive freeze thaw cycles. Kindly generate aliquots to avoid product failure caused by repeated freezing and thawing.
SML1689
Eupatilin
from (Isolated from Artemisia sp.), ≥98% (HPLC), powder, lipophilic flavonoid
Sinonimo/i:
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one, 5,7-Dihydroxy-3′,4′,6-trimethoxyflavone, NSC 122413
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Cambia visualizzazione
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 101.00 |
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 407.00 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C18H16O7
Numero CAS:
Peso molecolare:
344.32
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated, protect from light
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Eupatilin, ≥98% (HPLC)
biological source
(Isolated from Artemisia sp.)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated, protect from light
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31
InChI
1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3
InChI key
DRRWBCNQOKKKOL-UHFFFAOYSA-N
Application
Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay.
Biochem/physiol Actions
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.
Flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties
Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
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Questo articolo | |||
|---|---|---|---|
| description ≥98% (HPLC) | description phyproof® Reference Substance | description ≥97% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥90.0% (HPLC) | assay ≥97% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. - | storage temp. room temp | storage temp. room temp |
| solubility DMSO: 20 mg/mL, clear | solubility - | solubility DMSO: >10 mg/mL | solubility DMSO: >5 mg/mL |
| storage condition protect from light, desiccated | storage condition - | storage condition - | storage condition protect from light, desiccated |
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Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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