SML1238

Ertapenem sodium

≥90% (HPLC), powder, carbopenem antibiotic

• Sinonimo/i: (4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium, ZD-443 sodium
• Formula empirica (notazione di Hill): C₂₂H₂₄N₃O₇S · Na
• Numero CAS: 153773-82-1
• Peso molecolare: 497.50
• Codice UNSPSC: 51111800
• NACRES: NA.77

Proprietà

• product name: Ertapenem sodium, ≥90% (HPLC)
• Livello qualitativo: 100
• Saggio: ≥90% (HPLC)
• Forma fisica: powder
• Condizioni di stoccaggio: desiccated; protect from light
• Colore: white to beige
• Solubilità: H₂O: 20 mg/mL, clear
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −70°C
• InChI: 1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1; ZXNAQFZBWUNWJM-HRXMHBOMSA-M

Descrizione

Applicazioni

Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.

Azioni biochim/fisiol

Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.

Ertapenem sodium exhibits its activity against several aerobic and anaerobic microorganisms and is more resistant to β-lactamase enzymes. It has been studied in the treatment of several infectious diseases.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable