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SML1016

Sigma-Aldrich

Camalexin

≥98% (HPLC)

Sinonimo/i:

3-(Thiazol-2-yl)-1H-indole, Camalexine

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CHF 512.00

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5 MG
CHF 97.30
25 MG
CHF 512.00

About This Item

Formula empirica (notazione di Hill):
C11H8N2S
Numero CAS:
Peso molecolare:
200.26
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

CHF 97.30


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Saggio

≥98% (HPLC)

Stato

powder

Colore

white to light brown

Solubilità

DMSO: 20 mg/mL, clear

Temperatura di conservazione

2-8°C

Stringa SMILE

C12=CC=CC=C1NC=C2C3=NC=CS3

InChI

1S/C11H8N2S/c1-2-4-10-8(3-1)9(7-13-10)11-12-5-6-14-11/h1-7,13H
IYODIJVWGPRBGQ-UHFFFAOYSA-N

Applicazioni

Camalexin has been used in quantification[1] and tolerance assays in Arabidopsis thaliana leaves.[2]

Azioni biochim/fisiol

Camalexin is a phytoalexin isolated from cruciferous plants that exhibits antibacterial, antifungal, antiproliferative and cancer chemopreventive activities.
Camalexin is a phytoalexin isolated from cruciferous plants that exhibits antibacterial, antifungal, antiproliferative and cancer chemopreventive activities. Apparently, camalexin increases the ROS levels and is more effective in aggressive prostate cancer cells that express high ROS levels. In Arabidopsis thaliana, camalexin and salicylic acid confer resistance to Phytophthora capsici.

Caratteristiche e vantaggi

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Hector R Huarte et al.
Plants (Basel, Switzerland), 9(9) (2020-09-24)
The association among environmental cues, ethylene response, ABA signaling, and reactive oxygen species (ROS) homeostasis in the process of seed dormancy release is nowadays well-established in many species. Alternating temperatures are recognized as one of the main environmental signals determining
Jhon Venegas-Molina et al.
Scientific reports, 10(1), 10319-10319 (2020-06-27)
The plant hormones salicylic acid (SA) and jasmonic acid (JA) regulate defense mechanisms capable of overcoming different plant stress conditions and constitute distinct but interconnected signaling pathways. Interestingly, several other molecules are reported to trigger stress-specific defense responses to biotic
Camalexin quantification in Arabidopsis thaliana leaves infected with Botrytis cinerea
Savatin DV, et al.
Bio-protocol, 5(2), e1379-e1379 (2015)
Siva K Malka et al.
Frontiers in plant science, 8, 2131-2131 (2018-01-10)
Glucosinolates (GLS) are a group of plant secondary metabolites mainly found in Cruciferous plants, share a core structure consisting of a β-thioglucose moiety and a sulfonated oxime, but differ by a variable side chain derived from one of the several
Zhiping Zhang et al.
Frontiers in microbiology, 11, 1824-1824 (2020-08-28)
Ceratocystis manginecans causes mango wilt with significant economic losses. In the infection court, cerato-platanin (CP) family proteins (CPPs) are believed to involve in pathogenesis but has not been determined in C. manginecans. To confirm this function, a CP protein (CmCP)

Articoli

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

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