Passa al contenuto
Merck

Vai a

SML0868

Purmorphamine

≥98% (HPLC), powder, Hedgehog signaling activator

Sinonimo/i:

2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine; 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Scegli un formato

Cambia visualizzazione
Voi/SKUDisponibilitàPrezzo
5 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 177.00
25 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 561.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C31H32N6O2
Numero CAS:
Peso molecolare:
520.62
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

CHF 177.00


Per conoscere la disponibilità, visualizza il carrello

​
Richiedi un ordine personalizzato
Servizio Tecnico
Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.
Permettici di aiutarti


Nome del prodotto

Purmorphamine, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

N7(CCOCC7)c1ccc(cc1)Nc2nc(nc5[n](cnc52)C6CCCCC6)Oc3c4c(ccc3)cccc4

InChI

1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChI key

FYBHCRQFSFYWPY-UHFFFAOYSA-N

Application

Purmorphamine has been used to study the consequences of upregulation of Hedgehog signalling pathway in Tupfel long fin strain Zebrafish.

Biochem/physiol Actions

Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor.
Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor. In various studies, purmorphamine has been shown to induce osteoblast differentiation, generate cardiomyocytes from human embryonic stem cells, increase the neuronal differentiation of a human striatal neural stem cell line, and to differentiate human umbilical cord mesenchymal stem cells (hUCMSCs) into motoneurons.

Confronta articoli simili

Visualizza il confronto per intero

Mostra le differenze

1 of 1

Questo articolo
540220540223Z744976
Purmorphamine ≥98% (HPLC)

Sigma-Aldrich

SML0868

Purmorphamine

Purmorphamine A cell-permeable activator of Hedgehog signaling that induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 (EC50 = 1 µM).

Sigma-Aldrich

540220

Purmorphamine

Purmorphamine InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells

Sigma-Aldrich

540223

Purmorphamine

Dial Thermometer temp. range 0—200 °F, diam. 3 in., stem L 48 in. ×

Z744976

Dial Thermometer

description

≥98% (HPLC)

description

A cell-permeable activator of Hedgehog signaling that induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 (EC50 = 1 µM).

description

InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells

description

temp. range 0—200 °F, diam. 3 in., stem L 48 in. ×

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

form

powder

form

solid

form

liquid

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 200 mg/mL

solubility

-

solubility

-

color

white to beige

color

off-white

color

-

color

-


Still not finding the right product?

Explore all of our products under Purmorphamine


Pittogrammi

Health hazard

Parola di avvertenza

Warning

Codici di pericolo

Hazard Classifications

Muta. 2

Classe di stoccaggio

11 - Combustible Solids

Che succede?

WGK 3

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable



Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documenti section.

Se ti serve aiuto, non esitare a contattarci Servizio Clienti

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti




Questions

  1. What is the stability of purmorphamine as solid and in solution of DMSO ?

    1 answer
    1. This product is not assigned an expiration date or retest schedule. Products that are robust and extremely stable in their original unopened container are not assigned an expiration date or retest schedule. These products will not have dating reported on either the label or the Certificate of Analysis. Products without an expiration or retest date are covered by a warranty period of 1 year from the date of product shipment. Full product dating information can be reviewed at the following link: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/190/408/product-dating-information-ms.pdf. Stability in solution has not been internally validated. Other sources recommend storing at -20°C and using it within 1 year. It is advised to aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

      Helpful?

Reviews

No rating value

Active Filters