regulated under CDSA - not available from Sigma-Aldrich Canada
Colore
colorless to yellow
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Azioni biochim/fisiol
Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell.[1]
Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity.
Docosahexaenoyl ethanolamide (DHEA), a lipid signaling molecule, binds to the rat brain CB1 receptor and exhibits anti-inflammatory and organ protective activity.
Caratteristiche e vantaggi
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells
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