SML0288

Nepafenac

≥98% (HPLC)

• Sinonimo/i: 2-Amino-3-benzoyl-benzeneacetamide, AHR 9434, AL 6515
• Formula empirica (notazione di Hill): C₁₅H₁₄N₂O₂
• Numero CAS: 78281-72-8
• Peso molecolare: 254.28
• NACRES: NA.77
• PubChem Substance ID: 329825296
• UNSPSC Code: 12352200
• MDL number: MFCD08067732
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: faintly yellow to dark yellow
• solubility: DMSO: ≥5 mg/mL
• storage temp.: room temp
• SMILES string: NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2
• InChI: 1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
• InChI key: QEFAQIPZVLVERP-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Descrizione

Biochem/physiol Actions

Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.

Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) used in opthamology.

Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.

Informazioni sulla sicurezza

• Pittogrammi: GHS09
• Parola di avvertenza: Warning
• Codici di pericolo: H410
• Avvertenze di sicurezza: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable