SAB4503779

Anti-phospho-Smad1 (pSer⁴⁶⁵) antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 52 kDa
• Reattività contro le specie: mouse, rat, human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: Q15797
• N° accesso UniProt: Q15797
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer465)
• Informazioni sul gene: human ... SMAD1(4086)

Descrizione

Descrizione generale

Smad1 (SMAD family member 1) is a transcriptional activator, that is located on human chromosome 4q31.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Smad1 around the phosphorylation site of Ser465.

Immunogen Range: 416-465

Azioni biochim/fisiol

SMAD (homologues of the Drosophila protein, mothers against decapentaplegic (Mad) and the Caenorhabditis elegans protein Sma) proteins have a major role in disease development and hence act as biologic prognostic factors in diseases. miR-345 represses the multiplication, invasion and migration of prostate cancer by downregulating Smad1.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable