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SAB2701800

Sigma-Aldrich

Anti-sox2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

cb236, sox2, wu:fb83g04, wu:fc14d07

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100 μL
CHF 446.00

CHF 446.00


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100 μL
CHF 446.00

About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

CHF 446.00


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Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

Reattività contro le specie

zebrafish, (Japanese Medaka)

tecniche

immunohistochemistry: suitable
western blot: suitable

N° accesso NCBI

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... sox2(378723)

Immunogeno

Recombinant protein containing a sequence corresponding to a region within amino acids 42 and 238 of sox2 according to NP_998283

Applicazioni

Suggested starting dilutions are as follows: IHC-Fr: 1:100-1:1000, IHC-P: Assay-dependent dilution, WB: Assay-dependent dilution, IHC-Wm: 1:50-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Azioni biochim/fisiol

Transcriptional activator. May function as a switch in neuronal development.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pittogrammi

Exclamation markEnvironment

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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eLife, 9 (2021-01-01)
Defective primary cilia cause a range of diseases known as ciliopathies, including hearing loss. The etiology of hearing loss in ciliopathies, however, remains unclear. We analyzed cochleae from three ciliopathy mouse models exhibiting different ciliogenesis defects: Intraflagellar transport 88 (Ift88)
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Mechano-sensory hair cells (HCs), housed in the inner ear cochlea, are critical for the perception of sound. In the mammalian cochlea, differentiation of HCs occurs in a striking basal-to-apical and medial-to-lateral gradient, which is thought to ensure correct patterning and

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