T-cells stimulated with SEB produce high levels of IFN-γ, while PHA-stimulated T-cells produce little or no IFN-γ. For more information, refer to the reference at the following link: https://pmc.ncbi.nlm.nih.gov/articles/PMC1906565/#:~:text=%2Dcells%20(Fig.-,1).,compared%20to%20CD4+%20T%2Dcells
S4881
Staphylococcal enterotoxin B from Staphylococcus aureus
Sinonimo/i:
Enterotoxin B, Staphylococcal, SEB
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1 MG
CHF 338.00
5 MG
CHF 1’340.00
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Cambia visualizzazione
1 MG
CHF 338.00
5 MG
CHF 1’340.00
About This Item
Prodotti consigliati
contiene
sodium phosphate buffer as balance
Livello qualitativo
Composizione
Protein, ~25% Lowry
Disponibilità
not available in USA
Impurezze
Staphylococcal enterotoxin A (SEA), essentially free
applicazioni
metabolomics
vitamins, nutraceuticals, and natural products
Temperatura di conservazione
2-8°C
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Applicazioni
Staphylococcal enterotoxin B (SEB) which binds to MHC class II molecules and specific Vβ regions of T cell receptors (TCR), resulting in the activation of both monocytes/macrophages and T lymphocytes may be used as a superantigen and immune system activator. SEB may be used as a reference material in the development of SEB detection systems.
Azioni biochim/fisiol
Confezionamento
Package size based on protein content.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)
Oliver G Weingart et al.
Sensors (Basel, Switzerland), 12(2), 2324-2339 (2012-03-23)
Prevalent incidents support the notion that toxins, produced by bacteria, fungi, plants or animals are increasingly responsible for food poisoning or intoxication. Owing to their high toxicity some toxins are also regarded as potential biological warfare agents. Accordingly, control, detection
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Giselli Fernandes Asensi et al.
Microbial cell factories, 12, 32-32 (2013-04-09)
Staphylococcus aureus is unrestrictedly found in humans and in animal species that maintain thermal homeostasis. Inadequate cleaning of processing equipment or inappropriate handling can contaminate processed food and cause severe food poisoning. Staphylococcal enterotoxin B (SEB), a potent superantigenic exotoxin
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What is the difference in effects on T-lymphocyte proliferation between PHA and SEB? Thank you
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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こんにちは、この商品の容量をお聞きしたいのですが、1MGと表記されている場合、1miligramということでしょうか？ 溶かしてから調剤したいのですが。 溶かして調剤する際のプロトコルはあるのでしょうか？
1 answer-
Yes, the 1MG does stand for one milligram. The product is soluble in water at 4 mg/ml. It may also be dissolved in an aqueous buffer such as PBS. See the link below to the product information sheet for additional solution stability information:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/126/857/s4881pis.pdfHelpful?
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