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S2320

Sigma-Aldrich

Anti-SFRS2 antibody produced in rabbit

affinity isolated antibody, PBS solution, contains 0.09% sodium azide as preservative

Sinonimo/i:

Anti-Splicing Factor Arginine/serine-rich 2

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About This Item

Numero MDL:
MFCD07370501
Codice UNSPSC:
12352203

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

PBS solution

PM

antigen 25.6 kDa

contiene

0.09% sodium azide as preservative

Reattività contro le specie

human

tecniche

immunohistochemistry: suitable
western blot: suitable

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... SFRS2(6427)
mouse ... Sfrs2(20382)
rat ... Sfrs2(494445)

Immunogeno

synthetic peptide from the N-terminal region of SFRS2 conjugated to KLH.

Applicazioni

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Descrizione del bersaglio

SFRS2 (Splicing Factor Arginine/Serine-rich 2), alsoknown as PR264, SC35 (splicing component 35), and SRp30b, is a member of the SR protein family of splicing factors. SFRS2 regulates alternative splicing of pre-mRNA.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

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Matthew J Yousefzadeh et al.
EBioMedicine, 36, 18-28 (2018-10-04)
Senescence is a tumor suppressor mechanism activated in stressed cells to prevent replication of damaged DNA. Senescent cells have been demonstrated to play a causal role in driving aging and age-related diseases using genetic and pharmacologic approaches. We previously demonstrated
Rayna Rosati et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(24), 6509-6522 (2018-09-07)
Testosterone suppression in prostate cancer is limited by serious side effects and resistance via restoration of androgen receptor (AR) functionality. ELK1 is required for AR-dependent growth in various hormone-dependent and castration-resistant prostate cancer models. The amino-terminal domain of AR docks
Jana Kralovicova et al.
Nucleic acids research, 42(12), 8161-8173 (2014-06-20)
Splice-switching oligonucleotides (SSOs) have been widely used to inhibit exon usage but antisense strategies that promote removal of entire introns to increase splicing-mediated gene expression have not been developed. Here we show reduction of INS intron 1 retention by SSOs

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