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Key Documents

RAB1652

Sigma-Aldrich

Human PSP94 ELISA

for serum, plasma and cell culture supernatants

Sinonimo/i:

β-Microseminoprotein, Beta-microseminoprotein , IGBF, Immunoglobulin-binding factor, Prostate secretory protein of 94 amino acids

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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

human

tecniche

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... MSMB(4477)

Categorie correlate

Descrizione generale

The prostate secretory protein of 94 amino acids (PSP94), which is secreted by the prostate gland, is a small, cysteine-rich, and non-glycosylated protein. It is found abundantly in prostatic secretions and is a primary constituent of human semen. Lower expression of the PSP94 gene is observed in prostate cancer. PSP94 acts as a tumor suppressor and curbs metastasis. It also acts as an inhibitor of sperm motility and sperm acrosome reaction. The PSP94 gene is located on the human chromosome at 10q11.22.

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Altre note

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pittogrammi

Corrosion
GHS05

Avvertenze

Warning

Indicazioni di pericolo

H290

Consigli di prudenza

P234 - P390

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Bhakti R Pathak et al.
Asian journal of andrology, 12(5), 677-689 (2010-08-03)
The prostate secretory protein of 94 amino acids (PSP94) has been shown to interact with cysteine-rich secretory protein 3 (CRISP-3) in human seminal plasma. Interestingly, PSP94 expression is reduced or lost in the majority of the prostate tumours, whereas CRISP-3
Ashwani Kumar et al.
Journal of molecular biology, 397(4), 947-956 (2010-02-27)
Several recent genome-wide association studies have linked the human MSMB gene, encoding prostate secretory protein of 94 residues (PSP94), with prostate cancer susceptibility. PSP94 is one of the most abundant proteins from prostatic secretions and a primary constituent of human
Zhaohui Du et al.
International journal of cancer, 146(7), 1819-1826 (2019-06-22)
Latinos represent <1% of samples analyzed to date in genome-wide association studies of cancer. The clinical value of genetic information in guiding personalized medicine in populations of non-European ancestry will require additional discovery and risk locus characterization efforts across populations.

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