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Merck
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Documenti

N7160

Sigma-Aldrich

NAD-ADH Reagent Multiple Test Vial

for alcohol determination

Sinonimo/i:

Ethanol assay reagent

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About This Item

Codice UNSPSC:
41106305
NACRES:
NA.51

Livello qualitativo

Forma fisica

powder

Temperatura di conservazione

−20°C

Applicazioni

NAD-ADH Reagent Multiple Test Vial has been used to determine the alcohol content in blood. It has also been used to detect ethanol levels in mice.

Azioni biochim/fisiol

Alcohol dehydrogenase (ADH) catalyzes the oxidation of alcohol to acetaldehyde with the simultaneous reduction of nicotinamide adenine dinucleotide (NAD) to NADH. The consequent increase in absorbance at 340 nm is directly proportional to alcohol concentration in the sample.

Altre note

Vial contains ≥10 μmol of nicotinamide adenine dinucleotide (NAD) and ≥800 units of yeast alchohol dehydrogenase (ADH), buffer salts, and stabilizers.

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Resp. Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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ADH Cluster Genes, Genome-Wide Association Studies, and Alcohol Dependence
Park BL and Shin HD
Neuropathology of Drug Addictions and Substance Misuse, 520-530 (2016)
Ethanol Metabolism and Implications for Disease
Rajendram R, et al.
Neuropathology of Drug Addictions and Substance Misuse, 377-388 (2016)
Ajay C Donepudi et al.
Hepatology communications, 2(1), 99-112 (2018-02-07)
Alcoholic fatty liver disease (AFLD) is a major risk factor for cirrhosis-associated liver diseases. Studies demonstrate that alcohol increases serum bile acids in humans and rodents. AFLD has been linked to cholestasis, although the physiologic relevance of increased bile acids
Ana M Romero et al.
Neurotoxicity research, 29(1), 69-79 (2015-08-13)
Chronic alcohol consumption may cause neurodevelopmental and neurodegenerative disorders. Alcohol neurotoxicity is associated with the production of acetaldehyde and reactive oxygen species that induce oxidative DNA damage. However, the molecular mechanisms by which ethanol disturbs the DNA damage response (DDR)
Tatsuro Kumada et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26(3), 742-756 (2006-01-20)
The brains of fetal alcohol syndrome patients exhibit impaired neuronal migration, but little is known about the mechanisms underlying this abnormality. Here we show that Ca2+ signaling and cyclic nucleotide signaling are the central targets of alcohol action in neuronal

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